The results of univariate analysis showed that, in the EN intolerance group, the IAP, the PEEP value and APACHEII scores after 3 days of EEN implementation were higher than the EEN tolerance group, indicating a influencing factor of EEN intolerance (P<0.05). The results of multivariate analysis showed that IAP value was a risk factor for EEN intolerance (P<0.05). The ROC curve analysis result for IAP to predict EEN tolerance showed that the area under the curve for IAP value to predict EN tolerance was 0.856, the optimal cut-off value was 10.73 mmHg, the sensitivity was 95.10%, and the specificity was 89.60%.

The intra-abdominal pressure monitoring during the EEN in patients with severe pneumonia is a preferred method to guide the patients’ EEN.

The intra-abdominal pressure monitoring during the EEN in patients with severe pneumonia is a preferred method to guide the patients’ EEN.

To explore the diagnostic value of transcranial doppler (TCD) combined with carotid ultrasound (CU) in cerebral ischemic stroke (CIS).

A total of 68 patients with CIS who were treated in our hospital from September 2018 to September 2020 were selected as the research group, and another 68 patients with non-CIS admitted during the same period were selected as the reference group. Both groups underwent TCD and CU examinations to compare their diagnostic values.

There were no distinct differences concerning clinical data such as gender ratio, age, BMI value, smoking history, residence, and complications between the two groups (P > 0.05). The carotid artery intima-media thickening was reported at a markedly higher rate in the research group compared to the reference group (P < 0.001). It was indicated by the CU examination that the degree of carotid artery stenosis in the research group was more severe compared with the reference group (P < 0.05). The patients in the research group experienced more severe intracranial artery stenosis relative to the reference group by the TCD examination (P < 0.05). The plaque morphology of the research group was predominantly irregular, and the internal echoes were predominantly hypoechoic. The plaque morphology in the reference group was predominantly regular, and the internal echoes were predominantly isoechoic. There was remarkably higher incidence of the research group (78%) with ulcer as compared to the reference group (P < 0.05), and no marked difference was observed in the incidence of calcification (P > 0.05). The combined diagnostic approach was superior to TCD and CUS alone in the terms of accuracy, sensitivity and specificity (P < 0.001).

TCD combined with CU can greatly improve the diagnostic efficiency of CIS, and provide more evidence for clinical therapy. It deserves promotion and use.

TCD combined with CU can greatly improve the diagnostic efficiency of CIS, and provide more evidence for clinical therapy. It deserves promotion and use.

The goal of the present study was to explore and analyze the effect of comfort care on liver function and nursing satisfaction of patients with liver cirrhosis.

A total of 122 patients with liver cirrhosis addmitted to our hospital from June 2018 to June 2020 were equally divided into a general care group (GC) and a comfort care group (CC) according to the principle of randomization. Routine care intervention was given in the GC group, and the CC group received both comfort care intervention and routine care intervention. The care effects regarding liver function and nursing satisfaction, etc. were analyzed and compared between the two groups.

After care, both SAS score and SDS score in the two groups decreased, and the CC group had better scores of SAS and SDS as compared to the GC group (P<0.05). After care, the ALT and AST levels of the two groups all decreased. In the GC group, the ALT and AST demonstrated significantly better levels than those in the GC group (P<0.01). After care, each aspect in the CC group had better scores as compared to that in the GC group (P<0.05). After care, in the CC group, all the physiology, psychology, society and other index scores were significantly better than those in the GC group (P<0.05). Patients in the CC group had higher treatment compliance scores in comparison to patients in the GC group [(89.86±6.45) vs (64.46±13.75), P<0.01]. In the CC group, the nursing satisfaction (93.44%) was significantly higher than 78.69% in the GC group (P<0.01).

Comfort care is a preferred nursing method for patients with liver cirrhosis in terms of elimination of negative emotions, recovery of liver function, quality of life improvement, treatment compliance, and nursing satisfaction.

Comfort care is a preferred nursing method for patients with liver cirrhosis in terms of elimination of negative emotions, recovery of liver function, quality of life improvement, treatment compliance, and nursing satisfaction.

To analyze the clinical effect of fiberoptic bronchoscopy in treating severe ventilator-associated pneumonia (VAP).

From September 2018 to October 2019, 100 patients with severe VAP were recruited as the study cohort and randomly divided into two groups, with 50 patients in each group. The control group underwent routine treatment, such as lavage, and the experimental group underwent fiberoptic bronchoscopy. The effectiveness rates, recovery times, and respiratory mechanics indexes of the two groups were compared.

The total effective rate of the clinical treatment in the experimental group was significantly higher than it was in the control group (P < 0.05), and the recovery time in the experimental group was significantly shorter than it was in the control group (P < 0.05). After the treatment, the experimental group was significantly better than the control group (P < 0.05). After the treatment, the IL-8, CRP, and PCT levels in the experimental group were significantly lower than they were in the control group (P < 0.05).

Fiberoptic bronchoscopy can significantly improve the therapeutic effect of VAP, significantly shorten patients’ recovery times, significantly improve the respiratory mechanics-related indicators, and improve the therapeutic effect, so it is worthy of promotion.

Fiberoptic bronchoscopy can significantly improve the therapeutic effect of VAP, significantly shorten patients’ recovery times, significantly improve the respiratory mechanics-related indicators, and improve the therapeutic effect, so it is worthy of promotion.

This study focused on patients with chronic obstructive pulmonary disease (COPD) and aimed at investigating the effect of terbutaline plus doxofylline on their pulmonary function and quality of life.

Ninety COPD patients were divided by using a random number table into a control group (administration of doxofylline) and experimental group (administration of terbutaline combined with doxofylline), with 45 patients in each group. The therapeutic efficacy, pre- and post-treatment pulmonary function and the quality of life were compared between the control and experimental groups.

After treatment, patients in the experimental group had lower levels of interleukin-8, tumor necrosis factor α and C-reactive protein (all P<0.001), higher forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEVl/FVC (all P<0.001), and lower total score of COPD assessment test (P<0.05) compared with the control group.

Terbutaline combined with doxofylline for the treatment of COPD patients can efficiently decrease inflammatory factor levels, and bring them better pulmonary function and quality of life.

Terbutaline combined with doxofylline for the treatment of COPD patients can efficiently decrease inflammatory factor levels, and bring them better pulmonary function and quality of life.

This study explored and analyzed the application value of informatization-based extended care on children discharged with leukemia.

109 children receiving chemotherapy for acute leukemia in our hospital from January 2018 to January 2020 were selected as research subjects. The children were divided into the control group (n=53) and the observation group (n=56) on the basis of admission time point. The control-group children were given conventional nursing measures, and the observation-group children received informatization-based extended nursing care. Patients, self-care ability and their satisfaction with nursing care, and children’s quality of life, anxiety and depression between the two groups were compared prior and post intervention.

After intervention, the score in each dimension and the total scores of caring abilities in the two groups of patients increased remarkably than those before intervention (

), and the caring skills, health knowledge and the improvement of total score of nursing abilit informatization-based extended nursing care can effectively promote the nursing ability of parents on children with acute leukemia, improve the life quality of children and reduce their adverse psychological moods, which is conducive to improving the nursing satisfaction, and is worthy of clinical promotion.

This study analyzed the effect of multi-platform extended care on postoperative self-efficacy and quality of life in patients with osteoporotic vertebral compressive fracture (OVCF).

162 OVCF patients who underwent percutaneous vertebroplasty (PVP) or percutanous kyphoplasty (PKP) surgery in our hospital from January 2018 to June 2019 were classified into a control group (n=78) and an observation group (n=84) based on the admission time. The control group was given conventional health guidance and follow-up by telephone, and the observation group got multi-platform extended care. The postoperative incidence of re-fracture, Oswestry dysfunction index (ODI) before and after intervention, self-efficacy and quality of life were compared between the two groups.

Incidence of re-fracture in the observation group was higher than that of the control group (

). The ODI scores of the two groups 3, 6, and 12 months after operation were lower than those on discharge (

), and the observation group had lower OD scory of clinical promotion.

To explore the risk factors and prediction models of 28-day mortality in acute respiratory distress syndrome (ARDS) patients.

A total of 215 ARDS patients treated in our hospital were enrolled in this prospective observational study, including 70 patients who died within 28 days and were placed in the death group, and the remaining 145 patients who survived and were placed in the survival group. The laboratory examination indexes and critical scoring system scores were compared between the two groups. A Cox regression analysis was used to analyze the factors associated with 28-day mortality, and a receiver operating characteristic (ROC) curve was used to analyze the performance of the prediction models.

The ROC curve analysis showed that the erythrocyte distribution width (RDW), the neutrophil to lymphocyte ratio (NLR), the procalcitonin to albumin ratio (PAR), and the Murray lung injury score (MLIS) were effective at diagnosing the 28-day mortality, each with an area under the curve (AUC) of >0.5 (P<0.001). A multivariate Cox analysis showed that the RDW, NLR, PAR, and MLIS were independent predictors of 28-day mortality. The results of the multi-index joint prediction showed that the AUC of RDW+NLR+PAR+MLIS was 0.945 (95% CI 0.910-0.979), and the sensitivity was as high as 94.25%.

NLR, PAR, RDW, and MLIS are independent predictors of 28-day mortality, and their combined prediction can significantly improve the predictive ability of the 28-day mortality in ARDS patients.

NLR, PAR, RDW, and MLIS are independent predictors of 28-day mortality, and their combined prediction can significantly improve the predictive ability of the 28-day mortality in ARDS patients.