Aimed to evaluate the coexistence of bacterial and fungal diversity and their correlation with enzymatic activity in response to biochar. This study performed aerobic composting based on typical agricultural wastes of sheep manure with additive apple tree branch biochar at distinct concentration (0, 2.5, 5, 7.5, 10 and 12.5% corresponding from T1 to T6). The result demonstrated that appropriate amendment of biochar enriched bacterial diversity (1646-1686 OTUs) but interestingly decreased fungal diversity (542-630 OTUs) compared to control (1444 and 682 OTUs). Biochar addition enhanced all enzymatic activities and its correlation with bacterial was more complex than fungal community (786 and 359 connect edges). The dominant microbes comprised of Firmicutes (45.2-35.2%), Proteobacteria (14.0-17.5%), Basidiomycota (32.4-49.5%) and Ascomycota (11.3-37.5%) among all the treatments. Overall, biochar regulates the composting microenvironment by influencing the microbial diversity and associated enzymatic activities.Megasphaera hexnaoica is anaerobic bacteria who has well running reverse β-oxidation pathway. In previous study, the strain showed excellent production of medium chain carboxylic acids (MCCAs) using fructose as electron donor. In this study, chain elongation process study using lactate instead of fructose was conducted in M. hexnaoica fermentation. It was found that M. hexanoica can use lactate as electron donor in chain elongation process. 8.9 g/L caproate production was achieved in fermentation using lactate as sole electron donor. Compare to fructose condition, lactate as electron donor showed more than 3 times higher specific titer and specific productivity. In addition, when fructose and lactate were used as electron donor simultaneously, further improvement of MCCAs production was observed to achieve maximum caproate productivity of 20.9 g/L/day. Utilization of lactate as electron donor in M. hexanoica showed potential opportunity in chain elongation process.The aim of this study was to investigate the pretreatment of rice straw using cow breeding wastewater. The effects of filtering cow breeding wastewater through rice straw and microaerobic treatment on the pretreatment characteristics and methane production of rice straw were investigated. Generally, the filtration improved the pretreatment effect by adsorbing ammonium nitrogen and achieved higher solids loading for pretreatment. Although airtight treatment was optimal, the lignin removal and methane production of semi-sealed rice straw were only slightly lower than those of sealed rice straw. However, the results of open treatment were similar to those of the control. The maximum lignin removal and methane production reached 68.08% and 292.62 L/kg volatile solids (VS), respectively, for the filtered rice straw soaked in cow breeding wastewater again during pretreatment, and 61.26% and 274.18 L/kg VS, respectively, for the filtered rice straw pretreated directly without soaking.Biofuels are considered as a pre-eminent alternate to fossil fuels to meet the demand of future energy supply in a sustainable manner. Conventionally, they are produced from lignocellulosic raw materials. Saccharification of lignocellulosic raw materials for bioethanol production is a cumbersome process as compared to inulin-rich feedstocks. Various inulin-rich feedstocks, viz. jerusalem artichoke, chicory, dahlia, asparagus sp., etc. has also been exploited for the production of biofuels, viz. bioethanol, acetone, butanol, etc. The ubiquitous availability of inulin-rich feedstocks and presence of large amount of inulin makes them a robust substrate for biofuels production. Different strategies, viz. separate hydrolysis and fermentation, simultaneous saccharification and fermentation and consolidated bioprocessing have been explored for the conversion of inulin-rich feedstocks into biofuels. These bioprocess strategies are simple and efficient. The present review elaborates the prospective of inulin-rich feedstocks for biofuels production. Bioprocess strategies exploited for the conversion of inulin-rich feedstocks have also been highlighted.Enhanced biological phosphorus removal (EBPR) process is susceptible to the changed operation condition, which results in an unstable treatment performance. In this work, long-term effect of coagulants addition, aluminum salt for the reactor R1 and iron salt for the reactor R2, on EBPR systems was comprehensively evaluated. Results showed that during the initial 30 days’ coagulant addition, effluent chemical oxygen demand and phosphorus can be reduced below 25 and 0.5 mg·L-1, respectively. Further supply of metal salts would stimulate microbial extracellular polymeric substance excretion and induce reactive oxygen species accumulation, which destroyed the cell membrane integrity and deteriorated the phosphorus removal performance. Moreover, coagulants would decrease the relative abundance of Candidatus Accumulibacter while increase the relative abundance of Candidatus Competibacter, leading phosphors accumulating organisms in a disadvantage position. The results of this work might be valuable for the operation of chemical assisted biological phosphorus removal bioreactor.Micro-aeration was proven to be an environmentally friendly strategy for efficiently enhancing volatile fatty acids (VFAs) and lactic acid (LA) production. The roles of micro-aeration on mono-digestion of swine manure (SM) for VFAs production and co-digestion of SM with corn silage (CS) for LA production were investigated, respectively. In this study, micro-aeration increased the maximum VFAs concentration by 20.3% to 35.71 g COD/L, and shortened the time to reach the maximum from 18 days to 10 days. Micro-aeration limited the conversion of LA into VFAs, leading to LA accumulation effectively to be 26.08 g COD/L. Microbial community analysis suggested that Clostridium and Terrisporobacter were always the dominant bacteria with or without micro-aeration for VFAs production, but the relative abundance increased notably during the same period. However, Bifidobacterium, which could use the higher productivity metabolism pathway, i.e., Bifidum pathway to produce LA, increased from lower than 1% to 22.9% by micro-aeration.Cathode overpotential is a key factor in the energy efficiency of bioelectrochemical systems. In this study the aim is to demonstrate the role of applied current density and electrode storage capacity on cathode overpotential. To do so, eight reactors using capacitive granular activated carbon as cathode material were operated. Four reactors were controlled at -5 A m-2 and four at -10 A m-2. Additionally, to evaluate the electrode storage capacity, weekly charge/discharge tests were conducted for half of the reactors at each applied current density. Results show that cathode potential as high as -0.50 V vs. Ag/AgCl can be reached. Furthermore, the resulting low cathode overpotential is both dependent on applied current density and employment (or not) of charge/discharge tests reactors at -10 A m-2 without charge/discharge regimes did not result in increasing cathode potential whereas reactors at -5 A m-2 and at -10 A m-2 with charge/discharge regimes did.The aim of this work was to uncover the astaxanthin biosynthesis mechanism in Microcystis aeruginosa under optimum light quality, and promote astaxanthin production using this alga. Among purple, blue and red light, only purple light promoted M. aeruginosa cell growth compared with white light, due to up-regulating expression of the genes related with DNA replication. An increase was detected in the photosynthetic rate under purple light, which should be caused by the raised carotenoid content and up-regulation of the genes associated with light reaction and carbon fixation. Compared with white light, purple light increased the levels of β-carotene, zeaxanthin and astaxanthin by up-regulating expression of the genes related with methylerythritol-4-phosphate pathway (MEP) and astaxanthin biosynthesis. For red and blue light, they did not impact or declined the content of astaxanthin and its precursors. Therefore, purple light promoted M. aeruginosa cell growth and astaxanthin production by up-regulating related gene expression.In this study, four groups of microalgal-bacterial granules with averaged diameters of about 356, 760, 951 and 1,444 µm were used to investigate their characteristics and performance in treating wastewater. A strong correlation between extracellular polymeric substances of microalgal-bacterial granules and the granule size was observed. Moreover, granule size showed a positive effect on the specific organics removal rate, but being negative for ammonium and phosphorus removal. It appeared that granule size could be used as a useful index to reflect the synergistic interactions between microalgae and bacteria in terms of the abundances, distributions and functional species in the microalgal-bacterial granules. This study is expected to offer new insights into the size-dependent performances of microalgal-bacterial granules for wastewater treatment.Olive pomace oil (OPO), a by-product of olive oil industry, is directly consumed after refining. The novelty of this study consists of the direct use of crude high acidic OPO (3.4-20% acidity) to produce added-value compounds, using sn-1,3-regioselective lipases (i) low-calorie dietetic structured lipids (SL) containing caprylic (C80) or capric (C100) acids by acidolysis or interesterification with their ethyl esters, (ii) fatty acid methyl esters (FAME) for biodiesel, and (iii) sn-2 monoacylglycerols (emulsifiers), as by-product of FAME production by methanolysis. Immobilized Rhizomucor miehei lipase showed similar activity in acidolysis and interesterification for SL production (yields 47.8-53.4%, 7 h, 50℃) and was not affected by OPO acidity. Batch operational stability decreased with OPO acidity, but it was at least three-fold in interesterification that in acidolysis. Complete conversion of OPO into FAME and sn-2 monoacylglycerols was observed after 3 h-transesterification (glycerol stepwise addition) and lipase deactivation was negligeable after 11 cycles.Over the last two decades, the European School of Oncology (ESO) provided a career development program to young oncologists by offering extensive learning programs. In 2020, the College of ESO was established to provide a fully comprehensive educational pathway that covers the different needs of medical students, oncology fellows and specialists. The following educational activities were organized worldwide i) the masterclass in clinical oncology, ii) fellowships in clinical training centers, iii) the certificate of competence and advanced studies, iv) the medical student courses in oncology, v) the live e-sessions, vi) the refresher courses and vii) the Visiting Professor Program; and have reached areas where education is most needed and offered a variety of educational events in Europe, Eurasia, Middle East and Latin America. In this article, we present and evaluate the ESO educational programs devoted to young oncologists over the last 20 years.The association between polycyclic aromatic hydrocarbons (PAHs) exposure and hearing loss is rarely assessed. We aimed to evaluate the relationship of polycyclic aromatic hydrocarbons (PAHs) exposure and hearing loss among US adults and adolescents, and to explore the mediating role of systemic inflammation in the associations. Participants from the National health and Nutrition Examination Surveys (NHANES, 2001-2016) were included. Multiple logistic regression models were used to explore the associations between PAH metabolites and hearing loss. A total of 4200 adults and 1337 adolescents were included in the present analysis. For adults, we found positive association between urinary PAH metabolites and hearing loss, including total, speech-frequency and high-frequency hearing loss. The odds ratios (ORs) and 95% confidence intervals (CIs) for each one-unit increase in the log-transformed level of 3-Hydroxyfluorene (3-OHFlu), 2-Hydroxyfluorene (2-OHFlu) and 2 & 3-Hydroxyphenanthrene (2&3-OHPh) with total hearing loss were 1.