38-5.33) and anxiety symptoms (OR= 3.18, 95% CI 2.54-3.98), while controlling for gender, grade, living situation, and COVID-19 exposure; similarly, medium support was associated with higher prevalence of depression (OR= 2.79, 95% CI 2.48-3.15) and anxiety (OR= 2.19, 95% CI 1.94-2.48) symptoms.

This study indicates there is a higher prevalence of mental health problems among adolescents with medium and low levels of social support in China during the outbreak of COVID-19.

This study indicates there is a higher prevalence of mental health problems among adolescents with medium and low levels of social support in China during the outbreak of COVID-19.

Understanding and addressing the unique health and development needs of adolescent boys and young men (ABYM) is critical to achieving positive development outcomes for all genders. While major investments have been historically allocated toward adolescent girls and young women, a handful of approaches designed explicitly to reach ABYM have been successful. This review aims to understand the potential impact of mentoring interventions for ABYM on reproductive health (RH) knowledge and practices; social assets and soft skills; levels of gender-based and interpersonal violence; attitudes around gender equality; and substance use and financial vulnerability.

An electronic search of peer-reviewed and gray literature produced a review of 1,178 articles which yielded a total of 29 articles evaluating the 27 interventions included in the final review.

Mentoring approaches demonstrate promise for improving soft skills and social assets among ABYM-two factors that are thought to contribute to positive youth develtrated positive results.

We aimed to assess the prevalence of four cardiovascular risk factors (obesity, diabetes, excessive alcohol intake, and cigarette smoking) for parents and their adult children at the same approximate midlife age. We also evaluated associations of parents’ cardiovascular risk factors, childhood health exposures, and social contexts (i.e., family, school, and neighborhood) during adolescence with adult children’s cardiovascular health at midlife.

We used data from respondents at Wave V of the National Longitudinal Study of Adolescent to Adult Health who had corresponding parent (mostly mothers) data from Wave I. The final sample included 10,466 adult children with a mean age of 37.8years. Descriptive statistics and logistic regression models were estimated, accounting for the National Longitudinal Study of Adolescent to Adult Health sampling design.

At similar ages (i.e., 35-45 years) to their parents, adult children had higher rates of excessive drinking and obesity than their parents, lower rates of diascent social contexts and adult children’s cardiovascular risk factors.

The aim of the study was to examine the concurrent and longitudinal associations between adolescents’ text messaging frequency and mental health symptoms across 4 years of high school.

A total of 203 adolescents (aged 14-18years) consented and were provided smartphones across 4 years of high school. Using billing records, daily frequencies of text messaging were created for each year. Adolescents reported on their mental health symptoms (internalizing, externalizing, social problems, and inattention) each summer.

Multilevel analyses tested the between- and within-person associations between texting and mental health symptoms. Between-person analyses revealed an association only between externalizing symptoms and texting. Girls who texted more (vs. less) frequently reported more externalizing and inattention symptoms, whereas there were no significant associations for boys. There were no significant within-person concurrent associations between texting and symptoms. Autoregressive latent cross-lagged modolescence. Research on the content, rather than quantity, of texts and device use is necessary to understand the potential effects on development.

Many youth who engage in nonsuicidal self-injury (NSSI) go online for information, resources, and support. Although research has noted the potential benefits and risks of online NSSI activity, little is known about the NSSI-related needs that youth express on social media, and, importantly, when these posts occur. This study elucidates the nature of these NSSI-related needs and how they may vary temporally, by time of day or day of week.

A total of 3,500 posts made by 2,799 users of an international mental health-focused social network app were analyzed for the presence of NSSI-related needs. Posts were coded using a rubric that was developed using existing knowledge about youth’s online NSSI activity. Furthermore, prominently expressed needs were tested for associations with specific times of the day and days of the week.

Users’ frequently posted about suicidal ideation and behaviors, and difficult emotions; documented NSSI urges and interpersonal difficulties; and expressed feeling misunderstood and isolated. Furthermore, specific needs occurred more frequently during different times of the day (e.g., users were more likely to express suicidal ideation and behaviors just before midnight).

These findings have important implications for mental health professionals and policy makers. Youth who post about NSSI could benefit from the provision of tailored, evidence-based resources during times of need. Furthermore, clinicians may need to assess youth’s online activity to inform intervention strategies and meet their NSSI-related needs.

These findings have important implications for mental health professionals and policy makers. Youth who post about NSSI could benefit from the provision of tailored, evidence-based resources during times of need. Furthermore, clinicians may need to assess youth’s online activity to inform intervention strategies and meet their NSSI-related needs.

This study examined U.S. middle and high school student observations of electronic nicotine product (ENP) use in and around the school building and students’ normative perceptions of use among peers.

Adolescents and young adult participants enrolled in middle (n= 672) or high school (n= 962) were recruited from an online nationally representative panel and surveyed from November 2 to 15, 2018. They answered questions on observed ENP use in and around the school building as well as perceptions of use among peers.

Nearly one in five U.S. middle and high school students believed that at least half of their peers used ENPs. Confirming anecdotal reports, nearly six in 10 reported ever seeing someone use ENPs in or around their school, most often outside the school building and in bathrooms or locker rooms.

The findings of this study underscore the importance of targeted prevention strategies and education efforts to prevent and combat adolescent ENP use in and around schools.

The findings of this study underscore the importance of targeted prevention strategies and education efforts to prevent and combat adolescent ENP use in and around schools.

The association between erectile dysfunction (ED) and cardiovascular disease (CVD) is well known, the latter being an early independent risk factor that can appear up to 5 years before the onset of cardiovascular symptoms. The enzyme endothelial nitric oxide synthase (eNOS) could be implicated in its pathophysiology as an endogenous vasodilator. Our objective was to analyse the influence of variants of the eNOS gene, in the response to treatment of ED, in patients with CVD.

Observational, prospective study in patients with ED of the Cardiac Rehabilitation Programme. Demographic variables were collected (International Index of Erectile Function (IIEF), quality of sexual life (mSLQQ), anxiety and depression (HAD), along with cardiovascular risk factors (CVRF). Genetic analysis of polymorphisms T-786C, G894T of the eNOS gene was performed by RT-PCR with TaqMan probe, and the data were analysed using SPSS 25.

Patients (n=35, 60.8±8.44 years) showed a median CVD (IQR 1-3) with severe ED (IIEF-EF of 9.4±6.73 points) and a low perception of their quality of sexual life (-19.4±8.37 points). At the final visit (n=15), there were 71% responders to treatment with iPDE5, with a significant improvement in their ED (IIEF=49.4±17.29, IIEF-FE=18.5±9.60 scores) and of their quality of sexual life (7±12 scores), with a higher percentage of responders among the native homozygous genotypes -786-TT and 864-TT.

Variants of the NOS3 gene could influence the response to iPDE5. Full analysis of the patient sample will be required to confirm these preliminary results.

Variants of the NOS3 gene could influence the response to iPDE5. Full analysis of the patient sample will be required to confirm these preliminary results.

Electroconvulsive therapy (ECT) is an essential psychiatric service with an important role in treating older adults with severe or treatment-resistant depression. During the COVID-19 pandemic, ECT services have be constrained by infection control measures. We report a case of a 66-year-old female patient with a severe major depressive episode who had previously responded to right unilateral ECT and was treated with two modified accelerated intermittent theta-burst stimulation (aiTBS) protocols.

The two aiTBS courses consisted of eight daily sessions over five consecutive days, followed by gradual tapering, using 1,800 pulses per session pre-COVID-19 (first course), and 600 pulses per session during the pandemic (second course).

Moderate to severe baseline depressive symptoms reached remission levels after both courses.

The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.

The 600-pulses aiTBS treatment protocol reported here warrants further study and evaluation, but may be a potential option in cases where older adults with severe depressive symptoms cannot access ECT during the COVID-19 pandemic.

To investigate the impact of medication reviews using collegial mentoring and systematic clinical evaluation on psychotropic prescriptions, behavioral and psychological symptoms of dementia (BPSD), and activities of daily living (ADL).

Four-month multicenter, multicomponent, cluster-randomized, single-blinded controlled trial.

Thirty-three Norwegian nursing homes including 67 nursing home wards (clusters).

A total of 723 enrolled patients, of which 428 participated in the study; 217 were randomized to the intervention and 211 to care as usual (control).

The COSMOS intervention consisted of Communication, Systematic pain management, Medication reviews, Organization of activities, and Safety. During medication review, the nursing home physician evaluated treatment with colleagues systematically using the results from validated clinical assessments.

Mean changes from baseline to month 4 in the number of prescribed psychotropic drugs (antipsychotics, anxiolytics, hypnotics or sedatives, antidepressants, and antidementia drugs); Neuropsychiatric Inventory Nursing Home Version (NPI-NH) and Cornell Scale of Depression in Dementia (CSDD); Lawton and Brody’s Physical Self Maintenance Scale (PSMS).

Compared to control, the mean change in prescribed psychotropic drugs was reduced both in total and regular number, while mean changes in NPI-NH and CSDD scores did not differ between the groups. Mean change in PSMS showed improvement in the intervention group, and deterioration in the control group.

Medication reviews using collegial mentoring and systematic clinical evaluation led to safe deprescribing, as the reductions in psychotropic drug use did not negatively affect BPSD, while ADL improved.

Medication reviews using collegial mentoring and systematic clinical evaluation led to safe deprescribing, as the reductions in psychotropic drug use did not negatively affect BPSD, while ADL improved.